Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CDC25A | P30304 | 3/20 | 0.56 |
| ▸ | POLA1 | P09884 | 1/20 | 0.56 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.51 |
| ▸ | VDR | P11473 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997756 | 0.91 | CYP2C19 (0.63) | CYP2C19CYP2D6CDC25APOLA1INPP5D | |
| SCHEMBL7997759 | 0.91 | CYP2C19 (0.63) | CYP2C19CYP2D6CDC25APOLA1INPP5D | |
| SCHEMBL17817066 | 0.87 | CYP2C19 (0.66) | CYP2C19CYP2D6CDC25APOLA1INPP5D | |
| Hydrochloric Acid SCHEMBL8003237 | 0.86 | INPP5D (0.66) | CYP2C19CYP2D6CDC25APOLA1INPP5D | |
| Hydrochloric Acid SCHEMBL8003235 | 0.86 | INPP5D (0.66) | CYP2C19CYP2D6CDC25APOLA1INPP5D | |
| SCHEMBL17817283 | 0.86 | CDC25A (0.65) | CYP2C19CYP2D6CDC25APOLA1INPP5D | |
| SCHEMBL18541412 | 0.83 | BCHE (0.68) | CYP2C19CYP2D6CDC25APOLA1INPP5D | |
| SCHEMBL9580404 | 0.83 | BCHE (0.68) | CYP2C19CYP2D6CDC25APOLA1INPP5D | |
| SCHEMBL18541463 | 0.83 | BCHE (0.68) | CYP2C19CYP2D6CDC25APOLA1INPP5D | |
| SCHEMBL21206235 | 0.83 | BCHE (0.68) | CYP2C19CYP2D6CDC25APOLA1INPP5D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | CYP2C19 4800/4885CYP2D6 4407/4885CDC25A 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.