Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.85 |
| ▸ | MEN1 | O00255 | 3/20 | 0.85 |
| ▸ | POLB | P06746 | 1/20 | 0.85 |
| ▸ | BLM | P54132 | 1/20 | 0.85 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | RECQL | P46063 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.63 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19500968 | 0.86 | SOAT2 (0.74) | KMT2AMEN1POLBBLMCTDSP1 | |
| SCHEMBL8743155 | 0.85 | SOAT2 (0.82) | POLBALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL8743258 | 0.85 | SOAT2 (0.82) | POLBALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL2138777 | 0.85 | SOAT2 (0.82) | POLBALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL9388173 | 0.85 | SOAT2 (0.82) | POLBALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL541399 | 0.85 | SOAT2 (0.82) | POLBALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL282938 | 0.85 | SOAT2 (0.82) | POLBALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL8743011 | 0.85 | SOAT2 (0.82) | POLBALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL8742971 | 0.85 | SOAT2 (0.82) | POLBALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL8743085 | 0.85 | SOAT2 (0.82) | POLBALDH1A1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | KMT2A 411/4885MEN1 4785/4885POLB 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.