Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | PDE6D | O43924 | 1/20 | 0.56 |
| ▸ | PDE8A | O60658 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | PDE9A | O76083 | 1/20 | 0.56 |
| ▸ | PDE8B | O95263 | 1/20 | 0.56 |
| ▸ | PDE6A | P16499 | 1/20 | 0.56 |
| ▸ | PDE6G | P18545 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PDE6B | P35913 | 1/20 | 0.56 |
| ▸ | PDE6C | P51160 | 1/20 | 0.56 |
| ▸ | PDE1A | P54750 | 1/20 | 0.56 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.56 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.56 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.56 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728010 | 0.85 | PDE2A (0.70) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL175950 | 0.72 | PDE2A (1.00) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL20893121 | 0.71 | ADORA2A (0.47) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL22045209 | 0.70 | KDM4E (0.52) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL29379322 | 0.69 | PDE10A (0.74) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL14361375 | 0.69 | POLB (0.68) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL17817683 | 0.69 | KDM4E (0.59) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL9052411 | 0.68 | POLB (0.55) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL972909 | 0.68 | ADORA3 (0.53) | PDE2APDE6DPDE8APDE5APDE9A | |
| SCHEMBL23295676 | 0.68 | KDM4E (0.54) | PDE2APDE6DPDE8APDE5APDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | PDE2A 1728/4885PDE6D 2332/4885PDE8A 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.