SCHEMBL17817832

SCHEMBL17817832

Cc1ccc(C(=O)N(CCCO)CCCO)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NTRK2 Q16620 1/20 0.49
EGFR P00533 2/20 0.46
ERBB2 P04626 2/20 0.46
HPGD P15428 3/20 0.44
GAA P10253 1/20 0.44
MLYCD O95822 1/20 0.44
ALDH1A1 P00352 4/20 0.43
LMNA P02545 2/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.42
GSK3B P49841 1/20 0.41
NPC1 O15118 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
OPRM1 P35372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12947920 0.96 NTRK2 (0.46) NTRK2EGFRERBB2HPGDGAA
SCHEMBL7456186 0.89 ALDH1A1 (0.46) EGFRERBB2HPGDGAAMLYCD
SCHEMBL10455765 0.85 EGFR (0.62) EGFRERBB2HPGDGAAMLYCD
SCHEMBL11752532 0.84 EGFR (0.56) EGFRERBB2HPGDGAAMLYCD
SCHEMBL16681497 0.83 NTRK2 (0.50) NTRK2EGFRERBB2HPGDGAA
SCHEMBL13964228 0.82 EGFR (0.59) EGFRERBB2HPGDGAAMLYCD
SCHEMBL27899698 0.82 EGFR (0.55) EGFRERBB2HPGDGAAMLYCD
SCHEMBL5395972 0.81 NTRK2 (0.49) NTRK2EGFRERBB2HPGDGAA
SCHEMBL16681496 0.81 NTRK2 (0.49) NTRK2EGFRERBB2HPGDGAA
SCHEMBL7967022 0.81 MLYCD (0.64) EGFRERBB2HPGDGAAMLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9758470-B2 Bis(perfluoroether carboxylic acid alkyl)amino ester and method for producing the same UNIMATEC CO., LTD. (JP) 2017-09-12 US disclosed
US-20160194275-A1 BIS(PERFLUOROETHER CARBOXYLIC ACID ALKYL)AMINO ESTER AND METHOD FOR PRODUCING THE SAME UNIMATEC CO., LTD. (JP) 2016-07-07 US disclosed
EP-3031795-A1 BIS(PERFLUOROETHER ALKYL CARBOXYLIC ACID)AMINO ESTER AND METHOD FOR MANUFACTURING SAME Unimatec Co., Ltd. (JP) 2016-06-15 EP disclosed