Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL9451023 | 1.00 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL155992 | 0.97 | TSHR (0.42) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL514882 | 0.97 | TSHR (0.42) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL7994686 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL1091790 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL23069487 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL8633019 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL4830427 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL1092628 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL28296617 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111973537-A | Whitening and anti-acne facial cleanser and preparation method thereof | 黄立新 | 2020-11-24 | — | — | CN | claimed |
| CN-102604003-B | Self-layering organic-inorganic nano composite emulsion and method for preparing same | UNIV DALIAN POLYTECHNIC | 2014-07-09 | — | — | CN | claimed |
| CN-102604003-A | Self-layering organic-inorganic nano composite emulsion and method for preparing same | UNIV DALIAN POLYTECHNIC | 2012-07-25 | — | — | CN | claimed |
| CN-101514271-A | Polyacrylic ester wood lacquer emulsion and synthetic method thereof | LIAONING 113 GROUP CHEMICAL CO (CN) | 2009-08-26 | — | — | CN | claimed |
| CN-100441600-C | Inorganic nano-particle-containing nucleocapsid inorganic-organic composite pressure-sensitive adhesive emulsion, and its preparing method and use | HONGCHANG ADHESIVE TAPE FACTOR (CN) | 2008-12-10 | — | — | CN | claimed |
| CN-101249058-A | Anti-dandruff relieve itching hair washing cream liquid containing inorganic salt and Chinese medicine and preparation thereof | UNIV KUNMING SCIENCE & TECHNOLOGY (CN) | 2008-08-27 | — | — | CN | claimed |
| CN-101084870-A | Emulsifying salt type traditional Chinese herbs emulsion used for washing and caring hair and preparation method thereof | UNIV KUNMING SCIENCE & TECHNOLOGY (CN) | 2007-12-12 | — | — | CN | claimed |
| CN-1814629-A | Inorganic nano-particle-containing nucleocapsid inorganic-organic composite pressure-sensitive adhesive emulsion, and its preparing method and use | HONGCHANG ADHESIVE TAPE FACTOR (CN) | 2006-08-09 | — | — | CN | claimed |
| CN-1163570-C | Ammonia suppressing film for rice field | 中国科学院南京土壤研究所 | 2004-08-25 | — | — | CN | claimed |
| CN-1298916-A | Ammonia suppressing film for rice field | NANJING INST SOIL SCI CAS (CN) | 2001-06-13 | — | — | CN | claimed |
| US-20240148622-A1 | TOPICAL COMPOSITION FOR SKIN | SHISEIDO COMPANY, LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| CN-116970248-B | Amphoteric polyacrylamide modified PVC drainage pipe and preparation method thereof | 湖南联塑科技实业有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-116970248-A | Amphoteric polyacrylamide modified PVC drainage pipe and preparation method thereof | 湖南联塑科技实业有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2023190466-A1 | MODIFIER FOR POLYACETAL RESIN, POLYACETAL RESIN COMPOSITION, AND METHOD FOR PRODUCING MODIFIER FOR POLYACETAL RESIN | 株式会社カネカ | 2023-10-05 | — | — | WO | disclosed |
| CN-115884812-A | Cleaning composition | 株式会社资生堂 | 2023-03-31 | — | — | CN | disclosed |
| EP-0697212-A2 | Deodorant cosmetic composition superior in resistance to discoloration and dispersion | SHINAGAWA FUEL CO., LTD. (JP) | 1996-02-21 | — | — | EP | disclosed |
| CN-1026775-C | Low-foaming sodium nitrate and sodium nitrite anti-caking agent | DALIAN CHEMICAL INDUSTRY CO (CN) | 1994-11-30 | — | — | CN | disclosed |
| CN-1089935-A | Octadecyloxy phenyl acid derivative, its preparation method and optical isomer separation method thereof | HISAMITSU PHARMACEUTICAL CO (JP) | 1994-07-27 | — | — | CN | disclosed |
| CN-1071395-A | Low-foaming anti-caking agent for sodium nitrate and sodium nitrite | DALIAN CHEMICAL INDUSTRY CO (CN) | 1993-04-28 | — | — | CN | disclosed |
| CN-1069484-A | Octadecyloxy phenyl acid derivative, its preparation method and optical isomer separation method thereof | HISAMITSU PHARMACEUTICAL CO (JP) | 1993-03-03 | — | — | CN | disclosed |