Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL23069487 | 1.00 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL8633019 | 1.00 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL155992 | 0.97 | TSHR (0.42) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL514882 | 0.97 | TSHR (0.42) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL11220693 | 0.94 | PPARD (0.37) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL7994686 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL1092628 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL1781807 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL1091790 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 | |
| Ether SCHEMBL9451023 | 0.93 | TSHR (0.40) | TSHRPPARDALDH1A1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110050794-A | A kind of herbicidal composition and its preparation method and application | 广西化工研究院有限公司 | 2019-07-26 | — | — | CN | claimed |
| CN-103221505-B | Oilfield Treatment Fluids | BAKER HUGHES INC. (US) | 2016-05-11 | — | — | CN | claimed |
| CN-101565831-B | Cyclic renewable water-based cleaning agent and cyclic renewing technology | SHENZHEN KESH CHEMICAL INDUSTRY CO LTD | 2012-01-18 | — | — | CN | claimed |
| CN-112544627-B | Application of insecticidal composition in preventing and controlling cucumber thrips flavescens, chinese rose frankliniella occidentalis or mango tea Huang Ji horse | 江苏龙灯化学有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116458507-A | Medicament for improving defoliation ripening effect and yield of chemically topping cotton | 新疆农业大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-116326593-A | Acaricidal composition containing spirodiclofen and application thereof | 浙江省化工研究院有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116326588-A | Compound insecticidal and bactericidal composition containing pymetrozine | 盐城利民农化有限公司 | 2023-06-27 | — | — | CN | disclosed |
| EP-4025652-A1 | CALCIUM CARBONATE TREATED WITH FUNCTIONALIZED POLY- AND/OR PERFLUORINATED COMPOUNDS | Omya International AG (CH) | 2022-07-13 | — | — | EP | disclosed |
| CN-111094444-B | Aqueous polymer composition | 陶氏环球技术有限责任公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-2021043935-A1 | CALCIUM CARBONATE TREATED WITH FUNCTIONALIZED POLY- AND/OR PERFLUORINATED COMPOUNDS | OMYA INTERNATIONAL AG (CH) | 2021-03-11 | — | — | WO | disclosed |
| CN-111094444-A | Aqueous polymer composition | 陶氏环球技术有限责任公司 | 2020-05-01 | — | — | CN | disclosed |
| US-6730680-B2 | FUNGICIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI; AGRICULTURE, PLANT DISEASES | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-04 | — | — | US | disclosed |
| US-6645911-B2 | Using a 6-phenoxypyridyl-2-yl carboxamide compound | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-11 | — | — | US | disclosed |
| US-6559151-B2 | For controlling phytopathogenic fungi | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-06 | — | — | US | disclosed |
| US-6552026-B2 | Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-22 | — | — | US | disclosed |
| US-6380202-B1 | SELECTIVE FUNGICIDAL ACTIVITY AND HIGH SYSTEMICITY | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-30 | — | — | US | disclosed |
| US-6277857-B1 | EXCELLENT SELECTIVE FUNGICIDAL ACTIVITY AGAINST VARIOUS CROP PHYTOPATHOGENS | AMERICAN CYANAMID COMPANY | 2001-08-21 | — | — | US | disclosed |
| US-6255309-B1 | PLANTS | AMERICAN CYANOMID CO. | 2001-07-03 | — | — | US | disclosed |
| US-6204269-B1 | Fungicidal trifluoromethylalkylamino-triazolopyrimidines | AMERICAN CYANAMID CO. | 2001-03-20 | — | — | US | disclosed |
| US-6197802-B1 | FOR AGRICULTURE | AMERICAN CYANAMID CO. | 2001-03-06 | — | — | US | disclosed |