Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17819304 | 0.86 | ELANE (0.62) | ELANECYP2C9CYP3A4CTSKNOTUM | |
| SCHEMBL17819337 | 0.86 | ELANE (0.46) | ELANECYP2C9CYP3A4CTSK | |
| SCHEMBL17964358 | 0.86 | ELANE (0.47) | ELANECYP2C9CYP3A4CTSKNOTUM | |
| SCHEMBL17819319 | 0.81 | ELANE (0.43) | ELANECYP2C9CYP3A4CTSKNOTUM | |
| SCHEMBL17819345 | 0.79 | ELANE (0.64) | ELANECYP2C9CYP3A4CTSK | |
| SCHEMBL19639792 | 0.79 | ELANE (0.46) | ELANECYP2C9CYP3A4CTSKPOLB | |
| SCHEMBL19677885 | 0.79 | ELANE (0.61) | ELANECYP2C9CYP3A4CTSK | |
| SCHEMBL17819362 | 0.79 | ELANE (0.49) | ELANECYP2C9CYP3A4CTSK | |
| SCHEMBL17819301 | 0.78 | ELANE (0.59) | ELANECYP2C9CYP3A4CTSK | |
| SCHEMBL17819346 | 0.78 | ELANE (0.51) | ELANECYP2C9CYP3A4CTSKNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168101-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168101-A1 | NOVEL COMPOUNDS | ELANE, SERPINB1, MPO | ELANE 1/4885CYP2C9 2366/4885CYP3A4 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.