Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 12/20 | 0.40 |
| ▸ | ATM | Q13315 | 9/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17820057 | 0.97 | PIK3C3 (0.42) | PIK3C3ATMATR | |
| SCHEMBL17820553 | 0.94 | PIK3C3 (0.40) | PIK3C3ATMGAABTKNPC1 | |
| SCHEMBL17820263 | 0.93 | PIK3C3 (0.41) | PIK3C3ATMGAABTK | |
| SCHEMBL17819767 | 0.91 | PIK3C3 (0.43) | PIK3C3ATM | |
| SCHEMBL17820618 | 0.90 | PIK3C3 (0.43) | PIK3C3ATMGAAPRKDC | |
| SCHEMBL17820218 | 0.90 | PIK3C3 (0.40) | PIK3C3ATMGAANPC1RAB9A | |
| SCHEMBL17819894 | 0.90 | PIK3C3 (0.43) | PIK3C3ATM | |
| SCHEMBL17819895 | 0.88 | PIK3C3 (0.42) | PIK3C3ATMGAAATR | |
| SCHEMBL17819898 | 0.88 | PIK3C3 (0.42) | PIK3C3ATMGAAATR | |
| SCHEMBL17907115 | 0.88 | PIK3C3 (0.46) | PIK3C3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | PRMT7, RBBP7, RER1 | PIK3C3 3047/4885ATM 3209/4885GAA 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.