SCHEMBL17822291

SCHEMBL17822291

CC(=O)N[C@H]1[C@H](O[C@@H]2[C@H](O)[C@@H](O)[C@@H](OCCCCCN)O[C@@H]2CO)O[C@H](CO)[C@H](O)[C@@H]1O

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 3/20 0.69
LGALS8 O00214 2/20 0.69
LGALS4 P56470 2/20 0.69
MAPK1 P28482 1/20 0.65
CD69 Q07108 1/20 0.51
IFNG P01579 1/20 0.49
FGF1 P05230 1/20 0.49
FGF2 P09038 1/20 0.49
BMP2 P12643 1/20 0.49
VEGFA P15692 1/20 0.49
SFRP1 Q8N474 1/20 0.49
CHIA Q9BZP6 1/20 0.48
ALDH1A1 P00352 1/20 0.47
THRB P10828 1/20 0.47
IGF2R P11717 2/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SIGLEC7 Q9Y286 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17832654 1.00 LGALS3 (0.69) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL17822271 1.00 LGALS3 (0.69) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL17832730 0.94 LGALS8 (0.61) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL19404728 0.94 LGALS3 (0.64) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL19614256 0.94 LGALS8 (0.61) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL17822272 0.93 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL19614147 0.93 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL17832655 0.93 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL19614152 0.93 LGALS8 (0.60) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL18608298 0.92 LGALS8 (0.67) LGALS3LGALS8LGALS4MAPK1CD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10188718-B2 Vaccines against Streptococcus pneumoniae serotype 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2019-01-29 US disclosed
EP-3230297-B1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX PLANCK GESELLSCHAFT (DE) 2018-10-17 EP disclosed
US-20170333545-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-11-23 US disclosed
EP-3230297-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-10-18 EP disclosed
WO-2016091399-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170333545-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 NEU4, PA2G4, STT3B LGALS3 82/4885LGALS8 169/4885LGALS4 12/4885
US-10188718-B2 Vaccines against Streptococcus pneumoniae serotype 4 NEU4, PA2G4, STT3B LGALS3 82/4885LGALS8 169/4885LGALS4 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.