Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MGMT | P16455 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433541 | 0.92 | NUDT1 (0.47) | NUDT1PRKDCIKBKBMAPTCYP1A2 | |
| SCHEMBL12602972 | 0.82 | CYP3A4 (0.44) | NUDT1KDM4EALDH1A1POLBMAP2K7 | |
| SCHEMBL17822433 | 0.81 | LMNA (0.56) | PRKDCCYP1A2CYP2D6CRHBPCRHR2 | |
| SCHEMBL13650791 | 0.79 | CTSK (0.61) | NUDT1PRKDCIKBKBMAPTCYP1A2 | |
| SCHEMBL13650825 | 0.76 | MAPT (0.54) | NUDT1PRKDCIKBKBMAPTCYP1A2 | |
| SCHEMBL19548102 | 0.76 | NUDT1 (0.63) | NUDT1PRKDCIKBKBMAPTCYP1A2 | |
| SCHEMBL13650785 | 0.76 | NUDT1 (0.54) | NUDT1PRKDCIKBKBMAPTCYP1A2 | |
| SCHEMBL14849909 | 0.75 | SMN1; SMN2 (0.42) | MAPTCYP1A2CYP2D6CTSKGAA | |
| Hydrochloric Acid SCHEMBL17822432 | 0.74 | NUDT1 (0.61) | NUDT1PRKDCIKBKBMAPTCYP1A2 | |
| SCHEMBL9643516 | 0.74 | GAA (0.56) | NUDT1PRKDCIKBKBMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170319456-A1 | HAIR COLOURANTS COMPRISING TETRAAMINOPYRIMIDINE DERIVATES | HENKEL AG & CO. KGAA (DE) | 2017-11-09 | — | — | US | disclosed |
| EP-3229770-A1 | HAIR COLOURANTS COMPRISING TETRAAMINOPYRIMIDINE DERIVATES | Henkel AG & Co. KGaA (DE) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016091455-A1 | HAIR COLOURANTS COMPRISING TETRAAMINOPYRIMIDINE DERIVATES | HENKEL AG & CO. KGAA (DE) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170319456-A1 | HAIR COLOURANTS COMPRISING TETRAAMINOPYRIMIDINE DERIVATES | KRT18, DPYD, H1-4 | NUDT1 286/4885PRKDC 109/4885IKBKB 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.