Helicide

Helicide

SCHEMBL17822698

O=Cc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@@H](O)[C@H]2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.69
KDM4E B2RXH2 1/20 0.58
POLB P06746 1/20 0.58
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.58
G6PD P11413 1/20 0.58
MAPK1 P28482 1/20 0.58
ADRA1A P35348 1/20 0.58
PTGS2 P35354 1/20 0.58
AKR1B1 P15121 1/20 0.57
DPP4 P27487 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Helicide SCHEMBL23457333 1.00 TYR (0.69) TYRKDM4EPOLBGAAMAPT
Helicide SCHEMBL5030879 1.00 TYR (0.69) TYRKDM4EPOLBGAAMAPT
Helicide SCHEMBL467669 1.00 TYR (0.69) TYRKDM4EPOLBGAAMAPT
Helicide SCHEMBL9426962 1.00 TYR (0.69) TYRKDM4EPOLBGAAMAPT
Helicide SCHEMBL987981 1.00 TYR (0.69) TYRKDM4EPOLBGAAMAPT
SCHEMBL6842994 0.99 TYR (0.67) TYRKDM4EPOLBGAAMAPT
SCHEMBL6842995 0.99 TYR (0.67) TYRKDM4EPOLBGAAMAPT
SCHEMBL9189048 0.88 KDM4E (0.59) TYRKDM4EPOLBGAAMAPT
SCHEMBL16785945 0.88 TYR (0.87) TYRKDM4EPOLBGAAMAPT
SCHEMBL17366540 0.88 TYR (0.87) TYRKDM4EPOLBGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119564710-A Application of helicid in antidepressant 张袁祥 2025-03-07 CN claimed
CN-118873543-A Aerosol matrix, application thereof and aerosol generating device 深圳芳芯科技有限公司 2024-11-01 CN claimed
CN-118852562-A Defect chiral covalent organic framework and preparation method and application thereof 华南师大(清远)科技创新研究院有限公司 2024-10-29 CN claimed
CN-118845667-A Co-supported helicid-rosmarinic acid co-solubilised solid dispersion and preparation method thereof 云南中医药大学 2024-10-29 CN claimed
CN-118512392-A Preparation method of photo-stable sulfadiazine sodium injection 湖南湘易康制药有限公司 2024-08-20 CN claimed
CN-118063364-A Compound containing condensed amino (sulfur) urea structure, preparation method and application thereof 中国农业大学 2024-05-24 CN claimed
CN-118063358-A 1-Hydroxy-1-sodium sulfonate structure-containing compound and preparation method and application thereof 中国农业大学 2024-05-24 CN claimed
CN-114381484-B Application of UGT85A1 or RrUGT3 in catalyzing various substrates to generate glycoside compounds 山东大学 2024-04-19 CN claimed
CN-219935665-U Auxiliary device for measuring content of helicid 云南广福药业有限公司 2023-10-31 CN claimed
CN-112934192-B sugar-Schiff base functional material, preparation method thereof and application of material in glycopeptide enrichment 中国科学院大连化学物理研究所 2023-07-21 CN claimed
CN-116425812-A Bean curd fruit glycoside extraction process 云南广福药业有限公司 2023-07-14 CN claimed
CN-115073351-B Preparation method of 3,3' -bisindolyl methane 南京工业大学 2023-04-25 CN claimed
CN-115724737-A Preparation method of alpha-fluoro-beta-hydroxy ester compound 南京工业大学 2023-03-03 CN claimed
CN-115591008-A Spray-type liquid wound-protecting dressing and preparation method thereof 上海炫鑫医药科技有限公司(CN) 2023-01-13 CN claimed
CN-115348867-A Locally applicable lysate (Ly) of dedifferentiated cells of the plant helichrysum france for eliminating or reducing skin inflammation 化工产品开发公司SEPPIC 2022-11-15 CN claimed
CN-113244150-B Preparation containing helicid and preparation method and application thereof 西南林业大学 2022-11-04 CN claimed
CN-115073351-A Preparation method of 3,3' -bis-indolyl methane 南京工业大学 2022-09-20 CN claimed
CN-115011685-A Endogenous competitive RNA regulation network significantly related to helicid antidepressant effect 皖南医学院第一附属医院(皖南医学院弋矶山医院) 2022-09-06 CN claimed
CN-112725205-B Saccharomyces strain and screening method and application thereof 淮阴工学院 2022-05-17 CN claimed
CN-112934192-A sugar-Schiff base functional material, preparation method thereof and application of material in glycopeptide enrichment 中国科学院大连化学物理研究所 2021-06-11 CN claimed