Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17953985 | 1.00 | PTPN1 (0.35) | PTPN1ALDH1A1TDP1TSHRCHRM1 | |
| SCHEMBL11561306 | 0.81 | CA1 (0.34) | TSHRACE2 | |
| SCHEMBL21968568 | 0.81 | ENPEP (0.37) | — | |
| SCHEMBL1784139 | 0.80 | TSHR (0.44) | TDP1TSHRCHRM1ACE2 | |
| SCHEMBL15249703 | 0.80 | TSHR (0.44) | TDP1TSHRCHRM1ACE2 | |
| SCHEMBL12891365 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TDP1CHRM1 | |
| SCHEMBL17953984 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TDP1CHRM1 | |
| SCHEMBL9272361 | 0.79 | NAALAD2 (0.46) | ACE2 | |
| SCHEMBL1572858 | 0.79 | NAALAD2 (0.46) | ACE2 | |
| SCHEMBL9550634 | 0.79 | NAALAD2 (0.46) | ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20100168175-A1 | ATPENINS | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100168175-A1 | ATPENINS | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
| WO-2010069495-A1 | ATPENINS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-06-24 | — | — | WO | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| US-7186782-B2 | Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2007-03-06 | — | — | US | disclosed |
| US-20060041079-A1 | Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer | TSRC CORPORATION | 2006-02-23 | — | — | US | disclosed |
| US-6881797-B2 | Process for hydrogenation of conjugated diene polymer | TSRC CORPORATION (TW) | 2005-04-19 | — | — | US | disclosed |
| US-20040082727-A1 | Process for hydrogenation of conjugated diene polymer | TSRC CORPORATION (CN) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | PTPN1 4528/4885ALDH1A1 520/4885TDP1 3995/4885 |
| US-20100168175-A1 | ATPENINS | ATP5ME, ATP5MK, ATP5F1B | PTPN1 3393/4885ALDH1A1 3630/4885TDP1 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.