Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 3/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18112561 | 0.82 | CYP19A1 (0.36) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1784625 | 0.82 | LTB4R (0.35) | ALDH1A1MEN1MAPTKMT2AAOC3 | |
| SCHEMBL18112512 | 0.80 | CYP19A1 (0.35) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL7199262 | 0.80 | TXN (0.39) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1786817 | 0.76 | CNR1 (0.34) | HSD17B10 | |
| SCHEMBL13997749 | 0.73 | LTB4R (0.39) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL13997750 | 0.70 | LTB4R (0.41) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL9594349 | 0.70 | LTB4R (0.41) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL29730191 | 0.69 | TXN (0.41) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL6841224 | 0.69 | MCL1 (0.40) | ALDH1A1MAPTAOC3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117571-A1 | Transporter assay | WALLAC OY (FI) | 2011-05-19 | — | — | US | disclosed |
| EP-2215479-A1 | TRANSPORTER ASSAY | Wallac OY (FI) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009068751-A1 | TRANSPORTER ASSAY | WALLAC OY (FI) | 2009-06-04 | — | — | WO | disclosed |