Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXN | P10599 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 8/20 | 0.36 |
| ▸ | CA1 | P00915 | 8/20 | 0.36 |
| ▸ | CA2 | P00918 | 8/20 | 0.36 |
| ▸ | CA9 | Q16790 | 8/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29730191 | 0.90 | TXN (0.41) | TXNMEN1KMT2AMAPTCACNA1B | |
| SCHEMBL18112561 | 0.81 | CYP19A1 (0.36) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL1782379 | 0.80 | ALDH1A1 (0.33) | MEN1KMT2AMAPTCA1CA2 | |
| SCHEMBL1784625 | 0.80 | LTB4R (0.35) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL18112512 | 0.79 | CYP19A1 (0.35) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL1786817 | 0.75 | CNR1 (0.34) | — | |
| SCHEMBL13997749 | 0.71 | LTB4R (0.39) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL13997750 | 0.69 | LTB4R (0.41) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL9594349 | 0.69 | LTB4R (0.41) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL6841224 | 0.68 | MCL1 (0.40) | MAPTPOLBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030113769-A1 | Aminooxy functionalized oligomers, oligomer arrays and methods of using them | IONIS PHARMACEUTICALS, INC. | 2003-06-19 | — | — | US | disclosed |
| US-6576752-B1 | Oligonucleotide comprising a plurality of nucleotide units of given structure; useful for diagnostic, therapeutic and investigative purposes | ISIS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030113769-A1 | Aminooxy functionalized oligomers, oligomer arrays and methods of using them | RNGTT, RNMT, DCLRE1B | TXN 920/4885MEN1 4650/4885KMT2A 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.