SCHEMBL17824366

SCHEMBL17824366

CCOC(C)OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
ALDH1A1 P00352 3/20 0.48
PLA2G4B P0C869 1/20 0.46
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA12 O43570 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
KMT2A Q03164 1/20 0.44
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42
MAPK1 P28482 1/20 0.42
RXRA P19793 3/20 0.42
RXRB P28702 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8375375 0.93 CA1 (0.50) MAPTALDH1A1PDCD1CD274CA1
SCHEMBL17824454 0.92 MAPT (0.49) MAPTALDH1A1PLA2G4BPDCD1CD274
SCHEMBL9166635 0.88 TSHR (0.52) ALDH1A1PDCD1CD274KMT2ATP53
Terephthalic Acid SCHEMBL11348710 0.87 ALDH1A1 (0.52) MAPTALDH1A1PLA2G4BCA1CA2
SCHEMBL28515582 0.87 MAPT (0.44) MAPTALDH1A1PLA2G4BPDCD1CD274
SCHEMBL24600114 0.86 L3MBTL1 (0.49) MAPTALDH1A1PDCD1CD274CA1
SCHEMBL10880499 0.85 LMNA (0.59) MAPTALDH1A1PDCD1CD274CA1
SCHEMBL17797883 0.84 CA12 (0.46) MAPTALDH1A1PDCD1CD274CA1
SCHEMBL28515079 0.84 SMN1; SMN2 (0.47) MAPTKMT2ARXRARXRBTP53
Terephthalic Acid SCHEMBL8753677 0.84 MAPT (0.49) MAPTALDH1A1PLA2G4BCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3230376-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES Solutia Inc. (US) 2017-10-18 EP claimed
WO-2016094203-A1 POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES SOLUTIA INC. (US) 2016-06-16 WO claimed
CN-115397954-A Partial oxidation gasifier vitrified material 伊士曼化工公司 2022-11-25 CN disclosed