Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17824491 | 0.92 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL19684781 | 0.91 | S1PR1 (0.32) | S1PR1 | |
| SCHEMBL19684513 | 0.90 | LRRK2 (0.33) | S1PR1 | |
| SCHEMBL17824387 | 0.89 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL17824402 | 0.87 | JAK1 (0.34) | S1PR1 | |
| SCHEMBL17824423 | 0.86 | MAPT (0.32) | — | |
| SCHEMBL17824489 | 0.85 | — | — | |
| SCHEMBL17824483 | 0.84 | KCNH2 (0.33) | — | |
| SCHEMBL19684786 | 0.83 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL17832777 | 0.80 | CA12 (0.34) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230284-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-15 | — | — | EP | disclosed |
| EP-3230284-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-15 | — | — | EP | disclosed |
| US-10308650-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-04 | — | — | US | disclosed |
| US-10308650-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-04 | — | — | US | disclosed |
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATION AG (CH) | 2017-12-07 | — | — | US | disclosed |
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATION AG (CH) | 2017-12-07 | — | — | US | disclosed |
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATION AG (CH) | 2017-12-07 | — | — | US | disclosed |
| EP-3230284-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016091731-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | WO | disclosed |
| WO-2016091731-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308650-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | DDT, TST, ACHE | S1PR1 2300/4885 |
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, TST, ACHE | S1PR1 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.