Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.53 |
| ▸ | GABRP | O00591 | 5/20 | 0.51 |
| ▸ | GABRD | O14764 | 5/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.51 |
| ▸ | GABRE | P78334 | 5/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 3/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30276044 | 1.00 | KIF11 (0.53) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL262877 | 0.91 | KIF11 (0.44) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL12997524 | 0.87 | KIF11 (0.59) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31522706 | 0.87 | KIF11 (0.59) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL17080858 | 0.84 | CTSV (0.40) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL263127 | 0.84 | KIF11 (0.41) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL263052 | 0.84 | KIF11 (0.41) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30799378 | 0.83 | AHR (0.67) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19510163 | 0.83 | AHR (0.67) | KIF11GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL263322 | 0.82 | GABRP (0.39) | KIF11GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683453-B2 | Organic compounds with soluble groups | MERCK PATENT GMBH (DE) | 2020-06-16 | — | — | US | disclosed |
| US-10683453-B2 | Organic compounds with soluble groups | MERCK PATENT GMBH (DE) | 2020-06-16 | — | — | US | disclosed |
| EP-3230403-B1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | MERCK PATENT GMBH (DE) | 2019-10-09 | — | — | EP | disclosed |
| US-20170369773-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | UDC IRELAND LIMITED (IE) | 2017-12-28 | — | — | US | disclosed |
| US-20170369773-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | UDC IRELAND LIMITED (IE) | 2017-12-28 | — | — | US | disclosed |
| EP-3230403-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | Merck Patent GmbH (DE) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016091353-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | MERCK PATENT GMBH (DE) | 2016-06-16 | — | — | WO | disclosed |
| WO-2016091353-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | MERCK PATENT GMBH (DE) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369773-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | SLCO4C1, SLCO1B3, SLCO2B1 | KIF11 4314/4885GABRP 3261/4885GABRD 3503/4885 |
| US-10683453-B2 | Organic compounds with soluble groups | SLCO4C1, SLCO1B3, SLCO2B1 | KIF11 4314/4885GABRP 3261/4885GABRD 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.