Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.84 |
| ▸ | PLEC | Q15149 | 1/20 | 0.84 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ESRRG | P62508 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.61 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.61 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17825558 | 1.00 | POLB (0.84) | POLBPLECCTDSP1TDP1KDM4E | |
| SCHEMBL10026686 | 0.90 | POLB (0.86) | POLBPLECCTDSP1TDP1RAB9A | |
| SCHEMBL13475715 | 0.89 | POLB (0.84) | POLBPLECCTDSP1TDP1KDM4E | |
| SCHEMBL22925052 | 0.88 | POLB (0.82) | POLBPLECCTDSP1TDP1KDM4E | |
| SCHEMBL16035481 | 0.87 | CYP2D6 (0.77) | POLBPLECCTDSP1TDP1KDM4E | |
| SCHEMBL14907040 | 0.87 | CYP2D6 (0.77) | POLBPLECCTDSP1TDP1KDM4E | |
| SCHEMBL17832047 | 0.86 | MAPT (0.70) | POLBPLECCTDSP1TDP1KDM4E | |
| SCHEMBL12443154 | 0.85 | POLB (0.78) | POLBPLECCTDSP1TDP1KDM4E | |
| SCHEMBL19283325 | 0.83 | NPC1 (0.74) | POLBPLECCTDSP1TDP1KDM4E | |
| SCHEMBL19283324 | 0.83 | NPC1 (0.74) | POLBPLECCTDSP1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109096-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2025-04-03 | — | — | US | disclosed |
| EP-3230259-B1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | UNIV NEW YORK STATE RES FOUND (US) | 2024-04-03 | — | — | EP | disclosed |
| US-20220298103-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-09-22 | — | — | US | disclosed |
| US-11390580-B2 | Anti-fungals targeting the synthesis of fungal shingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-07-19 | — | — | US | disclosed |
| US-20200062698-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-02-27 | — | — | US | disclosed |
| US-20180141897-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-05-24 | — | — | US | disclosed |
| EP-3230259-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | The Research Foundation for The State University of New York (US) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094307-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11390580-B2 | Anti-fungals targeting the synthesis of fungal shingolipids | LSS, ERG28, CYP51A1 | POLB 4474/4885PLEC 1006/4885CTDSP1 1906/4885 |
| US-20220298103-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | POLB 4474/4885PLEC 1006/4885CTDSP1 1906/4885 |
| US-20180141897-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | POLB 4474/4885PLEC 1006/4885CTDSP1 1906/4885 |
| US-20200062698-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | POLB 4474/4885PLEC 1006/4885CTDSP1 1906/4885 |
| US-20250109096-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | POLB 4474/4885PLEC 1006/4885CTDSP1 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.