Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.82 |
| ▸ | PLEC | Q15149 | 1/20 | 0.82 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.82 |
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10026686 | 0.89 | POLB (0.86) | POLBTDP1PLECCTDSP1RAB9A | |
| SCHEMBL17825558 | 0.88 | POLB (0.84) | POLBTDP1PLECCTDSP1RAB9A | |
| SCHEMBL17825555 | 0.88 | POLB (0.84) | POLBTDP1PLECCTDSP1RAB9A | |
| SCHEMBL13475715 | 0.87 | POLB (0.84) | POLBTDP1PLECCTDSP1RAB9A | |
| SCHEMBL12443154 | 0.84 | POLB (0.78) | POLBTDP1PLECCTDSP1RAB9A | |
| SCHEMBL28484762 | 0.83 | RAB9A (0.74) | POLBTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11983704 | 0.82 | POLB (0.74) | POLBTDP1PLECCTDSP1RAB9A | |
| SCHEMBL1669543 | 0.80 | SIRT1 (0.72) | POLBTDP1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19283325 | 0.80 | NPC1 (0.74) | POLBTDP1PLECCTDSP1RAB9A | |
| SCHEMBL1669542 | 0.80 | SIRT1 (0.72) | POLBTDP1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |