SCHEMBL4338282

SCHEMBL4338282

O=C(Nn1ccnn1)c1ccccc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.50
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
ALDH1A1 P00352 4/20 0.50
HPGD P15428 4/20 0.50
MAPT P10636 3/20 0.50
USP2 O75604 1/20 0.50
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
GAA P10253 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MPO P05164 1/20 0.47
HIF1A Q16665 1/20 0.47
LMNA P02545 5/20 0.44
HTT P42858 4/20 0.44
NPC1 O15118 3/20 0.44
TP53 P04637 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8121292 0.78 LMNA (0.46) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL562017 0.75 KDM4E (0.50) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL11033030 0.73 KMT2A (0.68) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL316802 0.72 KCNMA1 (0.46) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL10635304 0.72 KDM4E (0.50) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL8815053 0.69
SCHEMBL7086187 0.69 KDM4E (0.55) KDM4EKMT2AALDH1A1HPGDMAPT
SCHEMBL11339136 0.68 KDM4E (0.65) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL170055 0.68
SCHEMBL6920212 0.68 KDM4E (0.49) KDM4EMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762441-B1 POLYURETHANE FOAMS BASED ON POLYETHER CARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-04-13 EP claimed
US-20200399466-A1 POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2020-12-24 US claimed
CN-111936542-A Polyurethane foams based on polyether carbonate polyols 科思创知识产权两合公司 2020-11-13 CN claimed
US-12398256-B2 Method for stabilizing thermoplastic recyclates, stabilized plastic compositions, and molding compounds and molded parts produced therefrom Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2025-08-26 US disclosed
EP-3762441-B1 POLYURETHANE FOAMS BASED ON POLYETHER CARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-04-13 EP disclosed
EP-3762441-A1 POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS Covestro Intellectual Property GmbH & Co. KG (DE) 2021-01-13 EP disclosed
US-20200399466-A1 POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2020-12-24 US disclosed
CN-111936542-A Polyurethane foams based on polyether carbonate polyols 科思创知识产权两合公司 2020-11-13 CN disclosed
WO-2019170590-A1 POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS COVESTRO DEUTSCHLAND AG (DE) 2019-09-12 WO disclosed
US-20130273367-A1 COMPOSITION FOR WIRE COATING MATERIAL, INSULATED WIRE, AND WIRING HARNESS AUTONETWORKS TECHNOLOGIES, LTD. (JP) 2013-10-17 US disclosed
US-20090054565-A1 Flame-Retardant plastics molding composition CLARIANT INTERNATIONAL LTD. 2009-02-26 US disclosed
US-5077328-A Heat resistance in presence of filler ASAHI DENKA KOGYO K.K. (JP) 1991-12-31 US disclosed
WO-1991002738-A1 ARYL ESTER AMIDE HALIDES OF PHOSPHONOUS ACID, ARYL ESTER AMIDES OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-07 WO disclosed
EP-0402889-A2 Polymeric polyalkyl-1-oxadiazaspirodecanes HOECHST AKTIENGESELLSCHAFT (DE) 1990-12-19 EP disclosed
WO-1990014349-A2 ARYLESTERS OF PHOSPHONOUS ACID, PROCESS FOR PREPARING THEM AND THEIR USE TO STABILIZE PLASTICS, IN PARTICULAR POLYOLEFIN MOULDING MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-29 WO disclosed
EP-0374761-A1 Process for the preparation of organophosphorus compounds of 4,4-diorganomagnesium biphenyl, and use of organophosphorus compounds as stabilizers for polymers, particularly polyolefine moulding compositions HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed
US-4705647-A TRIAZOLE ANTIOXIDANTS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1987-11-10 US disclosed
US-4663079-A OXIDATION RESISTANT MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1987-05-05 US disclosed
EP-0170063-A2 Copper-type conductive coating composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-02-05 EP disclosed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 US disclosed