SCHEMBL17825854

SCHEMBL17825854

O=C(Nc1cccc2ccccc12)Oc1ccc2ccccc2c1-c1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
TRPV1 Q8NER1 1/20 0.49
KDM4E B2RXH2 3/20 0.49
GAA P10253 2/20 0.49
HTR1A P08908 1/20 0.47
DRD2 P14416 1/20 0.47
MAPT P10636 2/20 0.47
CHRNB2 P17787 1/20 0.46
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
CHRNA4 P43681 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
PGR P06401 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19712932 0.85 TRPV1 (0.54) ALDH1A1HPGDTRPV1KDM4EGAA
SCHEMBL20483833 0.82 ALDH1A1 (0.50) ALDH1A1HPGDTRPV1KDM4EGAA
SCHEMBL9138035 0.81 GSK3B (0.48) ALDH1A1GAAMAPTRAB9APGR
SCHEMBL9138037 0.80 GSK3B (0.47) ALDH1A1HPGDKDM4EGAAMAPT
SCHEMBL4366187 0.79 GSK3B (0.59) ALDH1A1GAAMAPTRAB9APGR
SCHEMBL30448667 0.79 GSK3B (0.59) ALDH1A1GAAMAPTRAB9APGR
SCHEMBL1312094 0.75 TRPV1 (0.74) ALDH1A1HPGDTRPV1KDM4EGAA
SCHEMBL9621986 0.75 TRPV1 (0.58) ALDH1A1HPGDTRPV1KDM4EGAA
SCHEMBL1939486 0.75 GSK3B (0.49) ALDH1A1GAAMAPTRAB9APGR
SCHEMBL19712902 0.74 ALDH1A1 (0.45) ALDH1A1HPGDTRPV1KDM4EHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3230261-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS Covestro Deutschland AG (DE) 2017-10-18 EP disclosed
WO-2016091965-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS COVESTRO DEUTSCHLAND AG (DE) 2016-06-16 WO disclosed