SCHEMBL17825889

SCHEMBL17825889

C/C(=C\CCNC(=O)Oc1ccc2ccccc2c1-c1c(OC(=O)NCC/C=C(\C)C(=O)O)ccc2ccccc12)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 6/20 0.52
CES2 O00748 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 2/20 0.40
MAPT P10636 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 3/20 0.39
PGR P06401 1/20 0.39
GAA P10253 1/20 0.39
PTGS1 P23219 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20483693 0.94 NCEH1 (0.63) NCEH1
SCHEMBL20484011 0.92 NCEH1 (0.47) NCEH1CES2SMN1; SMN2HPGDMAPT
SCHEMBL20483896 0.92 NCEH1 (0.45) NCEH1HPGDMAPTALDH1A1KDM4E
SCHEMBL20483898 0.92 NCEH1 (0.45) NCEH1HPGDMAPTALDH1A1KDM4E
SCHEMBL20484103 0.91 NCEH1 (0.44) NCEH1CES2SMN1; SMN2HPGDMAPT
SCHEMBL20483934 0.91 NCEH1 (0.44) NCEH1CES2SMN1; SMN2HPGDALDH1A1
SCHEMBL20484009 0.91 NCEH1 (0.44) NCEH1CES2SMN1; SMN2
SCHEMBL20483932 0.89 NCEH1 (0.43) NCEH1CES2SMN1; SMN2MAPK1
SCHEMBL20484104 0.85 NCEH1 (0.43) NCEH1SMN1; SMN2KDM4EKMT2A
SCHEMBL20553821 0.84 NCEH1 (0.36) NCEH1CES2SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3622511-B1 HOLOGRAPHIC MEDIUM CONTAINING A PHOTOPOLYMERIC COATING FOR HOLOGRAPHIC EXPOSURE AND A LACQUER LAYER WITH HIGH RESISTANCE COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-04-27 EP disclosed
EP-3622512-B1 FILM STRUCTURE COMPRISING A PHOTOPOLYMER COATING FOR HOLOGRAPHIC EXPOSURE AND A LACQUER LAYER WITH HIGH RESISTANCE COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-04-27 EP disclosed
US-11267943-B2 Film structure containing a photopolymer layer for holographic exposure and a coating layer of high resistance COVESTRO DEUTSCHLAND AG (DE) 2022-03-08 US disclosed
US-20210292505-A1 FILM STRUCTURE CONTAINING A PHOTOPOLYMER LAYER FOR HOLOGRAPHIC EXPOSURE AND A COATING LAYER OF HIGH RESISTANCE COVESTRO DEUTSCHLAND AG (DE) 2021-09-23 US disclosed
US-20200166888-A1 HOLOGRAPHIC MEDIUM CONTAINING A PHOTOPOLYMER LAYER FOR HOLOGRAPHIC EXPOSURE AND A HIGHLY RESISTANT COATING LAYER COVESTRO DEUTSCHLAND AG (DE) 2020-05-28 US disclosed
EP-3622512-A1 FILM STRUCTURE CONTAINING A PHOTOPOLYMER LAYER FOR HOLOGRAPHIC EXPOSURE AND A COATING LAYER OF HIGH RESISTANCE Covestro Deutschland AG (DE) 2020-03-18 EP disclosed
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers COVESTRO DEUTSCHLAND AG (DE) 2019-03-26 US disclosed
EP-3401910-A1 HOLOGRAPHIC MEDIUM CONTAINING A PHOTOPOLYMERIC COATING FOR HOLOGRAPHIC EXPOSURE AND A LACQUER LAYER WITH HIGH RESISTANCE Covestro Deutschland AG (DE) 2018-11-14 EP disclosed
EP-3401909-A1 FILM STRUCTURE COMPRISING A PHOTOPOLYMER COATING FOR HOLOGRAPHIC EXPOSURE AND A LACQUER LAYER WITH HIGH RESISTANCE Covestro Deutschland AG (DE) 2018-11-14 EP disclosed
EP-3230261-B1 NAPHTHYL ACRYLATE AS WRITE MONOMERS FOR PHOTOPOLYMERS COVESTRO DEUTSCHLAND AG (DE) 2018-09-05 EP disclosed
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed
EP-3230261-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS Covestro Deutschland AG (DE) 2017-10-18 EP disclosed
WO-2016091965-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS COVESTRO DEUTSCHLAND AG (DE) 2016-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS NEFM, ACR, DIAPH1 NCEH1 4259/4885CES2 1466/4885SMN1; SMN2 3356/4885
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers NEFM, ACR, DIAPH1 NCEH1 4259/4885CES2 1466/4885SMN1; SMN2 3356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.