SCHEMBL7204775

SCHEMBL7204775

CONc1nc(N)nc2nc(C3C[C@H](O)[C@@H](CO)O3)[nH]c12

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.32
DNMT1 P26358 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1262483 0.73 PNP (0.44) ADRB1DNMT1
SCHEMBL7661689 0.71 LMNA (0.38) ADRB1DNMT1
SCHEMBL7195179 0.69 ADRB1 (0.53) ADRB1DNMT1
SCHEMBL4279999 0.69 GRIN2B (0.41) ADRB1DNMT1
SCHEMBL17825943 0.68 TSHR (0.50)
SCHEMBL12541692 0.68 HIF1A (0.33) ADRB1DNMT1
SCHEMBL9569360 0.66 ADORA3 (0.36)
SCHEMBL7204777 0.65 PNP (0.59) ADRB1DNMT1
SCHEMBL27093634 0.65 PNP (0.59) ADRB1DNMT1
SCHEMBL8088381 0.65 PNP (0.59) ADRB1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1151093-A4 ISOLATION OF NUCLEIC ACID MOLECULES INVITROGEN CORP (US) 2003-01-08 EP disclosed
WO-2000046366-A9 ISOLATION OF NUCLEIC ACID MOLECULES INVITROGEN CORP (US) 2002-02-14 WO disclosed
EP-1151093-A1 ISOLATION OF NUCLEIC ACID MOLECULES INVITROGEN CORPORATION (US) 2001-11-07 EP disclosed
WO-2000046366-A1 ISOLATION OF NUCLEIC ACID MOLECULES INVITROGEN CORPORATION (US) 2000-08-10 WO disclosed