Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779983 | 0.74 | CYP1A2 (0.43) | LMNAALDH1A1KDM4E | |
| SCHEMBL15869563 | 0.68 | LMNA (0.63) | LMNAPOLBHSD17B10RXFP1MEN1 | |
| SCHEMBL30026278 | 0.67 | STK17B (0.37) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL28960027 | 0.67 | STK17B (0.37) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL28960028 | 0.67 | STK17B (0.37) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL28898584 | 0.66 | NR1H2 (0.40) | LMNAPOLBMEN1GAAKMT2A | |
| SCHEMBL28898574 | 0.66 | SMN1; SMN2 (0.39) | LMNAPOLBMEN1GAAKMT2A | |
| SCHEMBL30024906 | 0.66 | NR1H2 (0.40) | LMNAPOLBMEN1GAAKMT2A | |
| SCHEMBL28898577 | 0.66 | NR1H2 (0.40) | LMNAPOLBMEN1GAAKMT2A | |
| SCHEMBL7771834 | 0.66 | AKR1B1 (0.35) | LMNAHSD17B10RXFP1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173641-B2 | 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173641-B2 | 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173641-B2 | 4-amino-1,2,3-benzoxathiazine-derivatives as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-21 | — | — | US | disclosed |
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-21 | — | — | US | disclosed |
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | BAYER CROPSCIENCE AG (DE) | 2010-10-21 | — | — | US | disclosed |
| WO-2010072310-A1 | 4-AMINO-1,2,3- BENZOXATHIAZINE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-07-01 | — | — | WO | disclosed |
| EP-2196461-A1 | 4-Amino-1,2,3-benzoxathiazine-derivatives as pesticides | Bayer CropScience AG (DE) | 2010-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267703-A1 | 4-Amino-1,2,3-benzoxathiazine-Derivatives as Pesticides | P2RX5, SLC1A5, P2RX4 | LMNA 4006/4885POLB 3800/4885HSD17B10 4358/4885 |
| US-20110118240-A2 | 4-Amino-1,2,3-Benzoxathiazine-Derivatives as Pesticides | P2RX5, P2RX4, SLC1A5 | LMNA 3998/4885POLB 3714/4885HSD17B10 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.