Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16229459 | 0.90 | SIRT2 (0.63) | SIRT2SIRT1ALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL1706647 | 0.87 | SIRT2 (0.80) | SIRT2SIRT1 | |
| SCHEMBL25132376 | 0.81 | KMT2A (0.69) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL3717363 | 0.79 | KMT2A (0.66) | SIRT2SIRT1ALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL3717360 | 0.79 | KMT2A (0.66) | SIRT2SIRT1ALDH1A1LMNAKMT2A | |
| SCHEMBL16229454 | 0.78 | SIRT2 (0.78) | SIRT2SIRT1ALDH1A1 | |
| SCHEMBL16229458 | 0.78 | SIRT2 (0.80) | SIRT2SIRT1 | |
| SCHEMBL12767874 | 0.77 | KMT2A (0.62) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL17826575 | 0.76 | SIRT2 (0.75) | SIRT2SIRT1 | |
| SCHEMBL16229388 | 0.76 | SIRT1 (0.81) | SIRT2SIRT1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365508-B2 | Aroyl thiourea derivatives | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2016-06-14 | — | — | US | disclosed |