Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TTR | P02766 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18137344 | 0.87 | NQO2 (0.48) | PTGS1KDM4ELMNAPTGS2MEN1 | |
| SCHEMBL17826850 | 0.82 | PTGS1 (0.57) | PTGS1KDM4ELMNAPTGS2MEN1 | |
| SCHEMBL18130124 | 0.82 | PTGS1 (0.57) | PTGS1KDM4ELMNAPTGS2MEN1 | |
| Resveratrol SCHEMBL3704258 | 0.74 | PTGS1 (1.00) | PTGS1KDM4ELMNAPTGS2MEN1 | |
| Resveratrol SCHEMBL19425 | 0.74 | PTGS1 (1.00) | PTGS1KDM4ELMNAPTGS2MEN1 | |
| Resveratrol SCHEMBL17629801 | 0.74 | PTGS1 (1.00) | PTGS1KDM4ELMNAPTGS2MEN1 | |
| Resveratrol SCHEMBL19426 | 0.74 | PTGS1 (1.00) | PTGS1KDM4ELMNAPTGS2MEN1 | |
| Resveratrol SCHEMBL20164915 | 0.74 | PTGS1 (1.00) | PTGS1KDM4ELMNAPTGS2MEN1 | |
| Cis-Resveratrol SCHEMBL1931746 | 0.74 | PTGS1 (1.00) | PTGS1KDM4ELMNAPTGS2MEN1 | |
| Resveratrol SCHEMBL2300985 | 0.74 | PTGS1 (1.00) | PTGS1KDM4ELMNAPTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031461-A1 | COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS | The President and Fellows of Harvard College (US) | 2016-06-15 | — | — | EP | disclosed |
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | BIOMOL INTERNATIONAL L.P. (US) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | SIRT1, SIRT7, SIRT5 | PTGS1 4289/4885KDM4E 640/4885LMNA 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.