Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | GUSB | P08236 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3333209 | 0.89 | NR4A2 (0.44) | AAK1CAMK2DNR4A2MTNR1AMTNR1B | |
| SCHEMBL3334978 | 0.89 | NR4A2 (0.44) | AAK1CAMK2DNR4A2MTNR1AMTNR1B | |
| SCHEMBL3334684 | 0.85 | AAK1 (0.45) | AAK1CAMK2DNR4A2MTNR1AMTNR1B | |
| SCHEMBL13301904 | 0.85 | CAMK2D (0.43) | AAK1CAMK2DNR4A2MTNR1AMTNR1B | |
| SCHEMBL14646918 | 0.84 | NR4A2 (0.47) | AAK1CAMK2DNR4A2MTNR1AMTNR1B | |
| SCHEMBL14646943 | 0.84 | CAMK2D (0.41) | AAK1CAMK2DNR4A2MTNR1AMTNR1B | |
| SCHEMBL17826908 | 0.84 | MTNR1A (0.54) | AAK1CAMK2DNR4A2MTNR1AMTNR1B | |
| SCHEMBL14646946 | 0.83 | KMT2A (0.46) | AAK1CAMK2DNR4A2MTNR1AMTNR1B | |
| SCHEMBL14646077 | 0.83 | NR4A2 (0.46) | NR4A2 | |
| SCHEMBL14646945 | 0.83 | CAMK2D (0.43) | AAK1CAMK2DNR4A2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121601-B1 | NOVEL INDOLE DERIVATIVES, METHODS FOR PREPARING SAME, AND USE THEREOF PARTICULARLY AS ANTIBACTERIAL AGENTS | Université Joseph Fourier (FR) | 2016-06-15 | — | — | EP | disclosed |