Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615998 | 0.79 | GRM4 (0.40) | GRM4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL7377972 | 0.76 | GRM4 (0.38) | GRM4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL31586242 | 0.76 | KDM4E (0.53) | TYMSKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL31165729 | 0.76 | GRM4 (0.41) | GRM4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL855507 | 0.76 | GRM4 (0.41) | GRM4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL24756927 | 0.76 | GRM4 (0.38) | GRM4KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL10164894 | 0.76 | EPAS1 (0.38) | GRM4ALDH1A1 | |
| SCHEMBL8189054 | 0.73 | ALDH1A1 (0.38) | GRM4KDM4EALDH1A1MAPT | |
| SCHEMBL10164899 | 0.72 | G6PD (0.38) | GRM4ALDH1A1MAPT | |
| SCHEMBL15724652 | 0.72 | EPHX2 (0.45) | GRM4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-B1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC (US) | 2016-06-15 | — | — | EP | disclosed |