Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13064199 | 0.86 | SREBF2 (0.47) | MAPTTP53ADORA3ALDH1A1NPC1 | |
| SCHEMBL13064531 | 0.82 | KMT2A (0.49) | MAPTTP53ADORA3ALDH1A1RAB9A | |
| SCHEMBL2614936 | 0.78 | CXCL12 (0.54) | CXCL12MAPTTP53ADORA3ALDH1A1 | |
| SCHEMBL2839700 | 0.76 | KDM4E (0.48) | CXCL12MAPTTP53ADORA3CTRC | |
| SCHEMBL2836839 | 0.74 | CTRC (0.45) | CXCL12MAPTTP53ADORA3CTRC | |
| SCHEMBL19539220 | 0.74 | ADORA2A (0.43) | MAPTTP53ALDH1A1CRHR1NPC1 | |
| SCHEMBL10272930 | 0.74 | KMO (0.50) | MAPTADORA3ALDH1A1NPC1RAB9A | |
| SCHEMBL2841068 | 0.73 | CTRC (0.44) | CXCL12MAPTTP53ADORA3CTRC | |
| SCHEMBL17826979 | 0.73 | SMN1; SMN2 (0.43) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL2609395 | 0.72 | CXCL12 (0.49) | CXCL12MAPTTP53ADORA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-B1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC (US) | 2016-06-15 | — | — | EP | disclosed |