Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17447752 | 0.86 | CHRM2 (0.51) | CHRM2CHRM4CHRM1CHRM3GBA1 | |
| SCHEMBL24696026 | 0.82 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3GBA1 | |
| SCHEMBL16855926 | 0.81 | FAAH (0.60) | CHRM2CHRM4CHRM1CHRM3ACKR3 | |
| SCHEMBL3709871 | 0.80 | FAAH (0.60) | CHRM2CHRM4CHRM1CHRM3GBA1 | |
| SCHEMBL16830462 | 0.78 | ACHE (0.60) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL30422174 | 0.78 | ACHE (0.60) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL23293544 | 0.78 | ACHE (0.60) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL30958238 | 0.78 | CHRM2 (0.52) | CHRM2CHRM4CHRM1CHRM3GBA1 | |
| SCHEMBL19475343 | 0.78 | MOK (0.72) | — | |
| SCHEMBL29111354 | 0.77 | GAA (0.66) | ALDH1A1KDM4ETSHRNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152692-B1 | COMPOUNDS WITH ANTI-CANCER ACTIVITY | CANBAS CO LTD (JP) | 2016-06-15 | — | — | EP | disclosed |