Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MPI | P34949 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DTYMK | P23919 | 2/20 | 0.47 |
| ▸ | CCNK | O75909 | 1/20 | 0.47 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709485 | 0.90 | FAAH (0.50) | FAAHKDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL3715140 | 0.84 | IDE (0.57) | KDM4EALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL23293544 | 0.82 | ACHE (0.60) | FAAHKDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL2422976 | 0.82 | PDGFRB (0.55) | CHRM2CHRM4CHRM1CHRM3ACHE | |
| SCHEMBL30422174 | 0.82 | ACHE (0.60) | FAAHKDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL16830462 | 0.82 | ACHE (0.60) | FAAHKDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL5383735 | 0.81 | FAAH (0.73) | FAAHKDM4EALDH1A1NPSR1LMNA | |
| SCHEMBL5594397 | 0.81 | MAPT (0.77) | KDM4EALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL17447752 | 0.81 | CHRM2 (0.51) | CHRM2CHRM4CHRM1CHRM3ACHE | |
| SCHEMBL17826997 | 0.80 | CHRM2 (0.50) | KDM4EALDH1A1NPSR1LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |