Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966567 | 0.83 | CYP1A2 (0.55) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17796948 | 0.79 | TAS2R14 (0.48) | MEN1KMT2APTPN1PTPN6PTPN11 | |
| SCHEMBL29803126 | 0.74 | RXFP1 (0.53) | MEN1KMT2APTPN1PTPN6PTPN11 | |
| SCHEMBL18358683 | 0.74 | RXFP1 (0.53) | MEN1KMT2APTPN1PTPN6PTPN11 | |
| SCHEMBL4610634 | 0.74 | PDK1 (0.65) | — | |
| SCHEMBL25026560 | 0.73 | MAPT (0.43) | MEN1KMT2APTPN1PTPN6PTPN11 | |
| SCHEMBL18197786 | 0.71 | EPHX1 (0.61) | MEN1KMT2ANPSR1TAS2R14MAPT | |
| SCHEMBL10364548 | 0.71 | MEN1 (0.41) | MEN1KMT2APTPN1PTPN6PTPN11 | |
| SCHEMBL7254538 | 0.71 | CYP1A2 (0.58) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11876682 | 0.71 | MAPT (0.41) | MEN1KMT2APTPN1PTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152692-B1 | COMPOUNDS WITH ANTI-CANCER ACTIVITY | CANBAS CO LTD (JP) | 2016-06-15 | — | — | EP | disclosed |