Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351032 | 0.80 | YTHDC1 (0.46) | YTHDC1SLC6A2SLC6A4G6PC1KDM4E | |
| SCHEMBL1536105 | 0.80 | YTHDC1 (0.46) | YTHDC1SLC6A2SLC6A4G6PC1KDM4E | |
| SCHEMBL1543222 | 0.74 | G6PC1 (0.48) | YTHDC1SLC6A2SLC6A4G6PC1MAPK1 | |
| SCHEMBL1543217 | 0.74 | G6PC1 (0.48) | YTHDC1SLC6A2SLC6A4G6PC1MAPK1 | |
| SCHEMBL1543221 | 0.74 | G6PC1 (0.48) | YTHDC1SLC6A2SLC6A4G6PC1MAPK1 | |
| SCHEMBL1543349 | 0.72 | YTHDC1 (0.51) | YTHDC1SLC6A2SLC6A4G6PC1KDM4E | |
| SCHEMBL1543347 | 0.72 | YTHDC1 (0.51) | YTHDC1SLC6A2SLC6A4G6PC1KDM4E | |
| SCHEMBL22659191 | 0.70 | YTHDC1 (0.42) | YTHDC1SLC6A2SLC6A4G6PC1KDM4E | |
| SCHEMBL17827173 | 0.67 | YTHDC1 (0.36) | YTHDC1SLC6A2SLC6A4G6PC1MEN1 | |
| Formic Acid SCHEMBL28594706 | 0.67 | YTHDC1 (0.43) | YTHDC1SLC6A2SLC6A4G6PC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031324-A2 | TRICYCLIC KINASE INHIBITORS | AbbVie Inc. (US) | 2016-06-15 | — | — | EP | disclosed |