SCHEMBL1782723

SCHEMBL1782723

CC(=O)C(O)CCCCC(C)C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
GPR84 Q9NQS5 3/20 0.41
FFAR1 O14842 1/20 0.41
BLM P54132 1/20 0.40
CA1 P00915 2/20 0.37
KDM4C Q9H3R0 2/20 0.36
KDM4A O75164 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KISS1R Q969F8 1/20 0.35
KDM1A O60341 1/20 0.35
PTPN1 P18031 1/20 0.33
RARB P10826 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1787012 0.98 GPR84 (0.45) LMNAGPR84FFAR1BLMCA1
SCHEMBL1782054 0.95 BLM (0.45) LMNAGPR84FFAR1BLMCA1
SCHEMBL1296220 0.84 CA1 (0.40) BLMCA1ALDH1A1TDP1KISS1R
SCHEMBL6494570 0.84 CA1 (0.40) BLMCA1ALDH1A1TDP1KISS1R
SCHEMBL6494567 0.84 CA1 (0.40) BLMCA1ALDH1A1TDP1KISS1R
SCHEMBL9059036 0.80 GPR84 (0.64) GPR84FFAR1CA1
SCHEMBL28704367 0.80 GPR84 (0.64) LMNAGPR84FFAR1BLMKDM4C
SCHEMBL1785261 0.80 GPR84 (0.64) GPR84FFAR1CA1
SCHEMBL27875262 0.80 GPR84 (0.64) GPR84FFAR1CA1
SCHEMBL1783437 0.79 GPR84 (0.42) LMNAGPR84FFAR1BLMCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 LMNA 1708/4885GPR84 77/4885FFAR1 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.