SCHEMBL1787012

SCHEMBL1787012

CC(=O)C(O)CCCCCC(C)C

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.45
FFAR1 O14842 1/20 0.45
LMNA P02545 1/20 0.40
KDM4C Q9H3R0 2/20 0.39
KDM4A O75164 1/20 0.39
PHF8 Q9UPP1 1/20 0.39
KDM2A Q9Y2K7 1/20 0.39
BLM P54132 1/20 0.39
CA1 P00915 2/20 0.36
TRPV1 Q8NER1 1/20 0.36
TRPA1 O75762 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KISS1R Q969F8 1/20 0.34
FAAH O00519 1/20 0.34
KDM1A O60341 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782723 0.98 LMNA (0.42) GPR84FFAR1LMNAKDM4CKDM4A
SCHEMBL1782054 0.93 BLM (0.45) GPR84FFAR1LMNAKDM4CBLM
SCHEMBL6494570 0.82 CA1 (0.40) BLMCA1ALDH1A1TDP1KISS1R
SCHEMBL6494567 0.82 CA1 (0.40) BLMCA1ALDH1A1TDP1KISS1R
SCHEMBL1296220 0.82 CA1 (0.40) BLMCA1ALDH1A1TDP1KISS1R
SCHEMBL15867154 0.81 GPR84 (0.68) GPR84FFAR1
SCHEMBL1785430 0.81 GPR84 (0.68) GPR84FFAR1
SCHEMBL22634111 0.81 GPR84 (0.68) GPR84FFAR1LMNAKDM4CKDM4A
SCHEMBL6555168 0.81 GPR84 (0.68) GPR84FFAR1LMNAKDM4CKDM4A
SCHEMBL1786126 0.81 GPR84 (0.68) GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 GPR84 77/4885FFAR1 229/4885LMNA 1708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.