SCHEMBL17828563

SCHEMBL17828563

CCCOc1ccc(-c2c3c(c(-c4ccc(OCCC)cc4)c4ccccc24)-c2ccc4c5c(ccc-3c25)-c2c-4c(-c3ccc(OCCC)cc3)c3cc4c(-c5ccc(OCCC)cc5)c5c(c(-c6ccc(OCCC)cc6)c4cc3c2-c2ccc(OCCC)cc2)-c2ccc3c4c(ccc-5c24)-c2c-3c(-c3ccc(OCCC)cc3)c3ccccc3c2-c2ccc(OCCC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.43
GAA P10253 5/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C19 P33261 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
TP53 P04637 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MGAM O43451 4/20 0.41
SI P14410 4/20 0.41
MGAM2 Q2M2H8 4/20 0.41
CTSV O60911 1/20 0.40
CTSL P07711 1/20 0.40
CYP2D6 P10635 1/20 0.39
CYP19A1 P11511 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17828553 0.94 CTSV (0.46) CYP1A2CYP2C19KDM4EALDH1A1MAPT
SCHEMBL17828550 0.80 ABL1 (0.46) KDM4EALDH1A1MAPTHPGDTP53
SCHEMBL14600342 0.77 PDK2 (0.44) PDE10AGAACYP1A2CYP2C19KDM4E
SCHEMBL5556584 0.76 CYP1A2 (0.47) PDE10AGAACYP1A2CYP2C19KDM4E
SCHEMBL14600408 0.76 PDK2 (0.43) PDE10AGAACYP1A2CYP2C19KDM4E
SCHEMBL14600417 0.76 PDK2 (0.43) PDE10AGAACYP1A2CYP2C19KDM4E
SCHEMBL14600347 0.75 PDK2 (0.43) PDE10AGAACYP1A2CYP2C19KDM4E
SCHEMBL14600484 0.75 PDK2 (0.43) PDE10AGAACYP1A2CYP2C19KDM4E
SCHEMBL134695 0.75 ACHE (0.47)
SCHEMBL14600390 0.74 PDK2 (0.47) PDE10AGAACYP1A2CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997717-B2 Organic electroluminescence device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-06-12 US disclosed
US-20160172601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed