Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829369 | 1.00 | TOP1 (0.52) | TOP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12579338 | 0.96 | TOP1 (0.56) | TOP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12210992 | 0.96 | TOP1 (0.56) | TOP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12210919 | 0.96 | TOP1 (0.56) | TOP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10051273 | 0.94 | TOP1 (0.55) | TOP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10051373 | 0.94 | TOP1 (0.55) | TOP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10051271 | 0.94 | TOP1 (0.55) | TOP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL25632423 | 0.94 | TOP1 (0.55) | TOP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10051372 | 0.94 | TOP1 (0.55) | TOP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10051329 | 0.93 | TOP1 (0.54) | TOP1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160172598-A1 | HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG CHEM, LTD. (KR) | 2016-06-16 | — | — | US | disclosed |
| US-20160172598-A1 | HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG CHEM, LTD. (KR) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160172598-A1 | HETERO RING COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | CRY1, CRY2, PER2 | TOP1 3349/4885MEN1 2678/4885KMT2A 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.