Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.58 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.57 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564592 | 0.95 | LTA4H (0.55) | CHRNB2CHRNA4CHRNB4CHRNA3LTA4H | |
| Hydrochloric Acid SCHEMBL10567449 | 0.94 | LTA4H (0.54) | CHRNB2CHRNA4CHRNB4CHRNA3LTA4H | |
| SCHEMBL10326531 | 0.83 | CHRNB4 (0.73) | CHRNB2CHRNA4CHRNB4CHRNA3LTA4H | |
| SCHEMBL10326918 | 0.83 | CHRNB4 (0.73) | CHRNB2CHRNA4CHRNB4CHRNA3LTA4H | |
| SCHEMBL10326970 | 0.83 | CHRNB4 (0.73) | CHRNB2CHRNA4CHRNB4CHRNA3LTA4H | |
| SCHEMBL14499009 | 0.81 | SCN4A (0.43) | — | |
| SCHEMBL13717874 | 0.80 | ALDH1A1 (0.47) | LTA4H | |
| SCHEMBL24388985 | 0.80 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA5 | |
| SCHEMBL29007952 | 0.79 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA5 | |
| SCHEMBL30181400 | 0.79 | CHRNB2 (0.68) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168111-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | DSM IP ASSETS B.V. (NL) | 2016-06-16 | — | — | US | disclosed |
| US-20160168111-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | DSM IP ASSETS B.V. (NL) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168111-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF PHENOLS OR THIOPHENOLS | CYP4B1, CYP4F3, CYP4F2 | CHRNB2 2244/4885CHRNA4 1840/4885CHRNB4 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.