Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CDYL2 | Q8N8U2 | 3/20 | 0.51 |
| ▸ | CDYL | Q9Y232 | 3/20 | 0.51 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 3/20 | 0.51 |
| ▸ | MIF | P14174 | 3/20 | 0.51 |
| ▸ | CD74 | P04233 | 2/20 | 0.51 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CBX7 | O95931 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830725 | 0.90 | POLB (0.52) | TP53LMNAIDO1POLBMAPT | |
| SCHEMBL17830721 | 0.89 | TP53 (0.59) | TP53LMNAPOLBMAPTUSP2 | |
| SCHEMBL17830723 | 0.88 | PKM (0.53) | TP53LMNAIDO1POLBMAPT | |
| SCHEMBL17830736 | 0.88 | MIF (0.52) | TP53LMNAIDO1POLBMAPT | |
| SCHEMBL17830715 | 0.86 | PIK3CB (0.54) | TP53IDO1POLBMAPTMIF | |
| SCHEMBL17830727 | 0.86 | IDO1 (0.55) | TP53LMNAIDO1POLBMAPT | |
| SCHEMBL17830735 | 0.84 | CCR2 (0.48) | TP53LMNAIDO1POLBMAPT | |
| SCHEMBL17830724 | 0.84 | IDO1 (0.51) | TP53LMNAIDO1POLBMAPT | |
| SCHEMBL17830729 | 0.83 | CYP1A2 (0.45) | TP53LMNAIDO1POLBMAPT | |
| SCHEMBL17830722 | 0.82 | RECQL (0.55) | TP53LMNAPOLBMAPTMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | CORNELL UNIVERSITY | 2016-06-16 | — | — | US | disclosed |
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | CORNELL UNIVERSITY | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | BCL6, BCL6B, BAZ2A | TP53 158/4885LMNA 3890/4885IDO1 1644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.