Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.52 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830745 | 0.91 | ALDH1A1 (0.56) | ALDH1A1ALDH3A1ALDH2MAPTHTT | |
| SCHEMBL17830746 | 0.88 | ALDH1A1 (0.51) | ALDH1A1ALDH3A1ALDH2CA1CA2 | |
| SCHEMBL17830710 | 0.88 | ALDH1A1 (0.64) | ALDH1A1ALDH3A1ALDH2PARK7MAPT | |
| SCHEMBL17830743 | 0.87 | ALDH1A1 (0.60) | ALDH1A1ALDH3A1ALDH2MAPTHTT | |
| SCHEMBL17830749 | 0.87 | CA1 (0.49) | ALDH1A1ALDH3A1ALDH2CA1CA2 | |
| SCHEMBL17830741 | 0.85 | ALDH1A1 (0.50) | ALDH1A1ALDH3A1ALDH2PARK7MAPT | |
| SCHEMBL17830744 | 0.85 | ALDH1A1 (0.55) | ALDH1A1ALDH3A1ALDH2CA1CA2 | |
| SCHEMBL17830754 | 0.84 | CASP1 (0.52) | ALDH1A1ALDH3A1ALDH2CA1CA2 | |
| SCHEMBL17830712 | 0.83 | PARK7 (0.60) | ALDH1A1ALDH3A1PARK7KMT2A | |
| SCHEMBL17830752 | 0.82 | ALDH1A1 (0.51) | ALDH1A1ALDH3A1ALDH2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | CORNELL UNIVERSITY | 2016-06-16 | — | — | US | disclosed |
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | CORNELL UNIVERSITY | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160166549-A1 | BCL6 INHIBITORS AS ANTICANCER AGENTS | BCL6, BCL6B, BAZ2A | ALDH1A1 4832/4885ALDH3A1 4762/4885ALDH2 4714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.