Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2671959 | 0.88 | CYP2D6 (0.50) | CYP3A4LMNAALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL4754949 | 0.83 | CYP2D6 (0.46) | CYP3A4LMNAALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL22238939 | 0.83 | RAB9A (0.51) | CYP3A4LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18417228 | 0.80 | CYP3A4 (0.43) | CYP3A4LMNAALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL8984070 | 0.78 | CYP3A4 (0.56) | CYP3A4LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22268268 | 0.77 | S1PR1 (0.42) | CYP3A4LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20647418 | 0.77 | CYP2D6 (0.40) | CYP3A4LMNAALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL16265270 | 0.77 | S1PR1 (0.39) | CYP3A4LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17197486 | 0.77 | ALDH1A1 (0.44) | CYP3A4LMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL16265238 | 0.74 | CYP3A4 (0.36) | CYP3A4LMNAALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160170110-A1 | THIN-FILM BROADBAND AND WIDE-ANGLE DEVICES FOR GENERATING AND SAMPLING POLARIZATION STATES | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2016-06-16 | — | — | US | disclosed |