Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2671959 | 0.95 | CYP2D6 (0.50) | CYP2D6CYP1A2CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL20647418 | 0.90 | CYP2D6 (0.40) | CYP2D6CYP1A2CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL22238939 | 0.90 | RAB9A (0.51) | CYP2D6CYP1A2CYP3A4RAB9ASMN1; SMN2 | |
| SCHEMBL18417228 | 0.89 | CYP3A4 (0.43) | CYP2D6CYP1A2CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL11887463 | 0.84 | HSD17B1 (0.38) | CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17831001 | 0.83 | CYP3A4 (0.46) | CYP2D6CYP1A2CYP3A4RAB9ASMN1; SMN2 | |
| SCHEMBL17197486 | 0.83 | ALDH1A1 (0.44) | CYP2D6CYP1A2CYP3A4RAB9ASMN1; SMN2 | |
| SCHEMBL16558134 | 0.82 | CYP3A4 (0.53) | CYP2D6CYP1A2CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL16558135 | 0.81 | NR5A1 (0.51) | CYP2D6CYP1A2CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL16558130 | 0.81 | NR5A1 (0.51) | CYP2D6CYP1A2CYP3A4CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8866997-B2 | Patterned electronic and polarization optical devices | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2014-10-21 | — | — | US | disclosed |
| US-20120105783-A1 | PATTERNED ELECTRONIC AND POLARIZATION OPTICAL DEVICES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2012-05-03 | — | — | US | disclosed |