SCHEMBL1783154

SCHEMBL1783154

CC(CC(=O)O)(c1ccccc1)c1cc(Br)ccc1OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.51
CCR5 P51681 2/20 0.48
LMNA P02545 2/20 0.47
USP2 O75604 1/20 0.46
LRRK2 Q5S007 5/20 0.45
PTGER1 P34995 5/20 0.43
CYP1A2 P05177 1/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
USP28 Q96RU2 1/20 0.43
USP25 Q9UHP3 1/20 0.43
ALDH1A1 P00352 1/20 0.43
RAB9A P51151 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4840135 0.87 PTGER1 (0.49) PTGDR2LRRK2PTGER1RXRARXRB
SCHEMBL5367447 0.79 PTGDR2 (0.60) PTGDR2CCR5LMNAUSP2LRRK2
SCHEMBL6530691 0.75 PTGDR2 (0.56) PTGDR2CCR5LMNAUSP2LRRK2
SCHEMBL5778498 0.75 CCR5 (0.55) PTGDR2CCR5LMNAUSP2LRRK2
SCHEMBL7076425 0.74 KMT2A (0.46) CCR5LMNAUSP28USP25ALDH1A1
SCHEMBL30955958 0.74 PTGER1 (0.54) CCR5LMNALRRK2PTGER1RXRA
SCHEMBL3726426 0.74 PTGER1 (0.54) CCR5LMNALRRK2PTGER1RXRA
SCHEMBL384896 0.72 FOLH1 (0.68) PTGDR2LMNALRRK2PTGER1ALDH1A1
SCHEMBL6452235 0.71 PTGDR2 (0.67) PTGDR2LMNAUSP2LRRK2ALDH1A1
SCHEMBL2537002 0.71 USP28 (0.60) PTGDR2CCR5LMNAPTGER1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110124903-A1 SOLID STATE FORMS OF FESOTERODINE INTERMEDIATES ACTAVIS GROUP PTC EHF (IS) 2011-05-26 US disclosed
US-20100217034-A1 Process for the Preparation of Fesoterodine ACTAVIS GROUP PTC EHF (IS) 2010-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217034-A1 Process for the Preparation of Fesoterodine ADRB3, FES, QDPR PTGDR2 2082/4885CCR5 3033/4885LMNA 4369/4885
US-20110124903-A1 SOLID STATE FORMS OF FESOTERODINE INTERMEDIATES FES, NISCH, RPS27A PTGDR2 1748/4885CCR5 4613/4885LMNA 4103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.