SCHEMBL17832018

SCHEMBL17832018

C=CCOc1c(OC)cccc1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.59
KDM4E B2RXH2 5/20 0.55
POLB P06746 2/20 0.55
LMNA P02545 2/20 0.51
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 1/20 0.50
KDM5A P29375 1/20 0.49
KDM5C P41229 1/20 0.49
MAPK1 P28482 1/20 0.47
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
TSHR P16473 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22215821 0.96 SMN1; SMN2 (0.55) SMN1; SMN2KDM4EPOLBLMNANPC1
SCHEMBL14176619 0.89 KDM4E (0.50) SMN1; SMN2KDM4EPOLBLMNANPC1
SCHEMBL1159573 0.88 KDM4E (0.49) SMN1; SMN2KDM4EPOLBLMNANPC1
SCHEMBL29340145 0.88 HSD17B10 (0.52) SMN1; SMN2KDM4EPOLBLMNANPC1
SCHEMBL19604880 0.86 SMN1; SMN2 (0.58) SMN1; SMN2KDM4EPOLBLMNANPC1
SCHEMBL3468787 0.86 KDM4E (0.56) SMN1; SMN2KDM4EPOLBLMNANPC1
SCHEMBL1628363 0.85 TSHR (0.50) SMN1; SMN2KDM4EPOLBLMNANPC1
SCHEMBL19604879 0.85 LMNA (0.56) SMN1; SMN2KDM4EPOLBLMNANPC1
SCHEMBL14172740 0.85 KDM4E (0.60) SMN1; SMN2KDM4EPOLBLMNANPC1
SCHEMBL668774 0.82 SMN1; SMN2 (0.58) SMN1; SMN2KDM4EPOLBLMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104230681-A Preparation method of 1,2,3-trimethoxy-5-allylbenzene CHENG WENFENG 2014-12-24 CN claimed
EP-4640794-A1 METHOD FOR PREPARING JET FUEL FROM LIGNIN OIL TotalEnergies OneTech (FR) 2025-10-29 EP disclosed
US-20250085264-A1 METHOD AND DEVICE FOR IMPROVING THE QUALITY AND TRACEABILITY OF ALCOHOLIC BEVERAGES, IN PARTICULAR WINES M&WINE (FR) 2025-03-13 US disclosed
EP-4457510-A1 METHOD AND DEVICE FOR IMPROVING THE QUALITY AND TRACEABILITY OF ALCOHOLIC BEVERAGES, IN PARTICULAR WINES M&Wine (FR) 2024-11-06 EP disclosed
WO-2023126615-A1 METHOD AND DEVICE FOR IMPROVING THE QUALITY AND TRACEABILITY OF ALCOHOLIC BEVERAGES, IN PARTICULAR WINES M&WINE (FR) 2023-07-06 WO disclosed
US-10307353-B2 1-phenylmono- or -polyhydroxypropane compounds, compositions and cosmetic uses thereof L'OREAL (FR) 2019-06-04 US disclosed
US-20170360665-A1 NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF L'OREAL (FR) 2017-12-21 US disclosed
US-20170360665-A1 NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF L'OREAL (FR) 2017-12-21 US disclosed
WO-2016092074-A1 NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF L'OREAL (FR) 2016-06-16 WO disclosed
CN-104230681-A Preparation method of 1,2,3-trimethoxy-5-allylbenzene CHENG WENFENG 2014-12-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10307353-B2 1-phenylmono- or -polyhydroxypropane compounds, compositions and cosmetic uses thereof GLA, PAH, P4HA1 SMN1; SMN2 4060/4885KDM4E 772/4885POLB 548/4885
US-20170360665-A1 NOVEL 1-PHENYLMONO- OR -POLYHYDROXYPROPANE COMPOUNDS, COMPOSITIONS AND COSMETIC USES THEREOF GLA, PAH, P4HA1 SMN1; SMN2 4265/4885KDM4E 762/4885POLB 661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.