Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27981723 | 0.87 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL19604880 | 0.87 | SMN1; SMN2 (0.58) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL9617754 | 0.87 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL3460333 | 0.86 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL30681592 | 0.86 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL17832018 | 0.86 | SMN1; SMN2 (0.59) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL3461299 | 0.86 | ALDH1A1 (0.57) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL19604879 | 0.86 | LMNA (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL11602955 | 0.84 | GABRA1 (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL22215821 | 0.83 | SMN1; SMN2 (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | SIMON FRASER UNIVERSITY (CA) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | KDM4E 332/4885ALDH1A1 4132/4885SMN1; SMN2 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.