Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728201 | 0.85 | CA1 (0.58) | MAPK1LTA4HESR2 | |
| SCHEMBL3695690 | 0.85 | CA1 (0.58) | MAPK1LTA4HESR2 | |
| SCHEMBL11938486 | 0.85 | CA1 (0.58) | MAPK1LTA4HESR2 | |
| SCHEMBL11938484 | 0.85 | CA1 (0.58) | MAPK1LTA4HESR2 | |
| SCHEMBL19728209 | 0.85 | CA1 (0.58) | MAPK1LTA4HESR2 | |
| SCHEMBL17832179 | 0.85 | TTR (0.50) | NPC1TP53MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL16372699 | 0.81 | TUBB4A (0.53) | MAPK1 | |
| SCHEMBL16372528 | 0.81 | ABL1 (0.55) | NPC1MAPK1RAB9APTGS1PTGS2 | |
| SCHEMBL17832171 | 0.79 | ESR1 (0.44) | NPC1TP53MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL17832221 | 0.78 | ACHE (0.44) | LMNAADRB2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362152-A1 | NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
| US-20170362152-A1 | NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF | L'OREAL (FR) | 2017-12-21 | — | — | US | disclosed |
| WO-2016092076-A1 | NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF | L'OREAL (FR) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362152-A1 | NOVEL 1,2-DIPHENYLETHYLENE GLYCOL COMPOUNDS FOR COMBATING AGING OF THE SKIN, AND COSMETIC USE THEREOF | GLA, DSG1, GPX1 | NPC1 1482/4885TP53 930/4885MAPK1 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.