SCHEMBL1783247

SCHEMBL1783247

O=C(NCC(F)(F)F)OCC(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.46
LMNA P02545 3/20 0.36
POLB P06746 2/20 0.36
KDM4E B2RXH2 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
FABP7 O15540 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12224099 0.85 HTT (0.42) HTTLMNAPOLBALDH1A1KMT2A
SCHEMBL24687424 0.84 HTT (0.48) HTTPOLBALDH1A1KMT2ASMN1; SMN2
SCHEMBL28096910 0.82 HTT (0.46) HTTKDM4ESMN1; SMN2NPC1RAB9A
SCHEMBL967570 0.80 HTT (0.45) HTTLMNAALDH1A1KMT2ASMN1; SMN2
SCHEMBL25447803 0.78 MEN1 (0.48) HTTPOLBALDH1A1KMT2ASMN1; SMN2
SCHEMBL30631642 0.78 SMN1; SMN2 (0.36) HTTLMNAPOLBKDM4EL3MBTL1
SCHEMBL7769996 0.77 HTT (0.42) HTTALDH1A1SMN1; SMN2NPC1RAB9A
SCHEMBL7769991 0.77 HTT (0.42) HTTSMN1; SMN2NPC1RAB9A
SCHEMBL12223162 0.77 ACHE (0.47) HTTL3MBTL1ALDH1A1KMT2AMEN1
SCHEMBL29362788 0.77 HTT (0.42) HTTPOLBALDH1A1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2316822-B1 PREPARATION OF CARBAMATES WITH SOLID CATALYSTS CONSEJO SUPERIOR INVESTIGACION (ES) 2016-10-26 EP disclosed
US-20150221987-A1 ELECTROLYTIC SOLUTION FOR NON-AQUEOUS SECONDARY BATTERY, AND NON-AQUEOUS ELECTROLYTIC SOLUTION SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2015-08-06 US disclosed
US-8735621-B2 Preparation of carbamates with solid catalysts CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2014-05-27 US disclosed
US-20110124902-A1 PREPARATION OF CARBAMATES WITH SOLID CATALYSTS Consejo Superior De Investigaciones Cientificas C/Serrano, 117 (ES) 2011-05-26 US disclosed
EP-2316822-A1 PREPARATION OF CARBAMATES WITH SOLID CATALYSTS Consejo Superior De Investigaciones Científicas (ES) 2011-05-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124902-A1 PREPARATION OF CARBAMATES WITH SOLID CATALYSTS ODC1, RCC1, OTC HTT 566/4885LMNA 1377/4885POLB 1407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.