Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 6/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 4/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18781 | 0.82 | ALDH1A1 (0.38) | IDH1ADRB1IDH2PIM1PIM2 | |
| SCHEMBL15102668 | 0.69 | IDH1 (0.36) | IDH1ADRB1IDH2PIM1PIM2 | |
| SCHEMBL18780 | 0.69 | IDH1 (0.36) | IDH1ADRB1IDH2PIM1PIM2 | |
| SCHEMBL29763275 | 0.69 | IDH1 (0.36) | IDH1ADRB1IDH2PIM1PIM2 | |
| SCHEMBL30144828 | 0.64 | IDH1 (0.46) | IDH1ADRB1IDH2PIM1PIM2 | |
| SCHEMBL2138274 | 0.64 | HDAC4 (0.56) | IDH1IDH2HDAC4TAS2R14 | |
| SCHEMBL28924087 | 0.64 | IDH1 (0.46) | IDH1ADRB1IDH2PIM1PIM2 | |
| SCHEMBL22637946 | 0.64 | IDH1 (0.45) | IDH1IDH2PIM1PIM2 | |
| SCHEMBL22637944 | 0.64 | IDH1 (0.45) | IDH1IDH2PIM1PIM2 | |
| SCHEMBL18186 | 0.63 | ALDH1A1 (0.39) | PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025460-A1 | OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |