Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | USP1 | O94782 | 3/20 | 0.40 |
| ▸ | WDR48 | Q8TAF3 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833281 | 0.89 | SYK (0.38) | ACP1USP1WDR48CYP1A2CYP3A4 | |
| SCHEMBL17833148 | 0.89 | GBA1 (0.39) | ACP1CYP1A2CYP3A4CYP2C19SYK | |
| SCHEMBL17829883 | 0.89 | ALDH1A1 (0.54) | ACP1ALDH1A1RAD52KMT2AMAPK1 | |
| SCHEMBL17833150 | 0.86 | CYP1A2 (0.41) | USP1WDR48CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17833235 | 0.85 | SYK (0.43) | ACP1SYKALDH1A1RAD52KMT2A | |
| SCHEMBL17833238 | 0.85 | TNKS (0.41) | ACP1SYKALDH1A1RAD52KMT2A | |
| SCHEMBL17833283 | 0.84 | SYK (0.40) | ACP1CYP1A2CYP3A4CYP2C19SYK | |
| SCHEMBL17833286 | 0.82 | SYK (0.38) | ACP1SYKALDH1A1RAD52KMT2A | |
| SCHEMBL17833154 | 0.82 | SYK (0.37) | ACP1USP1WDR48CYP1A2CYP3A4 | |
| SCHEMBL17833161 | 0.82 | KMT2A (0.40) | ACP1SYKALDH1A1RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |