Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083303 | 0.82 | CFTR (0.62) | GSK3BCXCR3TBXA2RCFTRLMNA | |
| SCHEMBL17824320 | 0.79 | CXCR3 (0.51) | GSK3BCXCR3TBXA2RCFTRLMNA | |
| SCHEMBL10573467 | 0.74 | TBXA2R (0.69) | TBXA2RCFTRLMNAMAPT | |
| SCHEMBL23361965 | 0.72 | NOD1 (0.56) | GSK3BCFTR | |
| SCHEMBL2217926 | 0.72 | LMNA (0.55) | LMNANPSR1 | |
| SCHEMBL10572147 | 0.72 | TBXA2R (0.66) | GSK3BTBXA2RCFTRLMNAMAPT | |
| SCHEMBL7999122 | 0.72 | TSHR (0.66) | MAPT | |
| SCHEMBL23362172 | 0.71 | NOD1 (0.66) | GSK3BTBXA2RCFTRMAPTP2RX4 | |
| SCHEMBL4288066 | 0.71 | KDM4E (0.65) | LMNA | |
| SCHEMBL28377078 | 0.70 | CFTR (0.67) | TBXA2RCFTRLMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016092327-A1 | PRO-SURVIVAL COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) | 2016-06-16 | — | — | WO | disclosed |